Can I Take These?

Can You Take Folate / Folic Acid and Vitamin C Together?

No documented interaction was identified between vitamin C and folate in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Folate / Folic Acid page and Vitamin C page for other reviewed interactions and reference information.

What the interaction means

Vitamin C's own NIH ODS fact sheet names only radiation therapy, chemotherapeutic agents, and statins as medication-interaction concerns, and does not mention folate or folic acid anywhere. Folate's own NIH ODS fact sheet names methotrexate, phenytoin, carbamazepine, valproate, and sulfasalazine as medication interactions, plus a masking effect on vitamin B12 deficiency, and does not mention vitamin C or ascorbic acid.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative fact sheets were checked directly, full text, in both directions.

What the sources say

Vitamin C — Health Professional Fact Sheet — NIH Office of Dietary SupplementsFolate — Health Professional Fact Sheet — NIH Office of Dietary Supplements

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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