Can You Take Levothyroxine and Vitamin C Together?
No documented interaction was identified between vitamin C and levothyroxine in the sources reviewed.
See the full Levothyroxine page and Vitamin C page for other reviewed interactions and reference information.
What the interaction means
Vitamin C's NIH fact sheet states its only documented medication-interaction concerns are with radiation therapy, chemotherapeutic agents, and statins; it does not mention levothyroxine. This project's existing published content on levothyroxine, drawn from levothyroxine's own authoritative sources (which document interactions with calcium, iron, and other minerals), does not document an interaction with vitamin C or ascorbic acid.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Vitamin C's own current authoritative fact sheet was checked directly, in full. This catalog's existing sourced content for levothyroxine was also checked for any mention of vitamin C or ascorbic acid; none was found.
What the sources say
Last reviewed 2026-08-24
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
Related interactions
- Levothyroxine and CalciumUse caution
- Levothyroxine and AtorvastatinInsufficient evidence
- Levothyroxine and IronUse caution
- Levothyroxine and CiprofloxacinInsufficient evidence
- Levothyroxine and SertralineMonitor
- Levothyroxine and Vitamin DInsufficient evidence
- Levothyroxine and WarfarinInsufficient evidence
- Levothyroxine and CreatineInsufficient evidence
- Levothyroxine and SpironolactoneInsufficient evidence
- Levothyroxine and St. John's WortInsufficient evidence
- Levothyroxine and CaffeineInsufficient evidence
- Levothyroxine and Vitamin KInsufficient evidence
- Levothyroxine and Vitamin B12Insufficient evidence
- Levothyroxine and CopperInsufficient evidence
- Levothyroxine and ZincInsufficient evidence
- Levothyroxine and PotassiumInsufficient evidence
- Levothyroxine and LisinoprilInsufficient evidence
- Levothyroxine and TurmericInsufficient evidence
- Levothyroxine and CoQ10 (Coenzyme Q10)Insufficient evidence
- Levothyroxine and DoxycyclineInsufficient evidence
- Levothyroxine and OmeprazoleMonitor
- Levothyroxine and MagnesiumMonitor
- Levothyroxine and MetforminInsufficient evidence
- Levothyroxine and MelatoninInsufficient evidence
- Levothyroxine and ProbioticsInsufficient evidence
- Levothyroxine and Omega-3 / Fish OilInsufficient evidence
- Levothyroxine and Vitamin EInsufficient evidence
- Levothyroxine and Folate / Folic AcidInsufficient evidence
- Levothyroxine and AshwagandhaMonitor
- Levothyroxine and LosartanInsufficient evidence
- Levothyroxine and AspirinMonitor
- Levothyroxine and AmlodipineInsufficient evidence
- Levothyroxine and EscitalopramInsufficient evidence
- Levothyroxine and IbuprofenInsufficient evidence
- Vitamin C and CiprofloxacinInsufficient evidence
- Vitamin C and LisinoprilInsufficient evidence
- Vitamin C and MagnesiumInsufficient evidence
- Vitamin C and PotassiumInsufficient evidence
- Vitamin C and St. John's WortInsufficient evidence
- Vitamin C and OmeprazoleInsufficient evidence
- Vitamin C and ProbioticsInsufficient evidence
- Vitamin C and CoQ10 (Coenzyme Q10)Insufficient evidence
- Vitamin C and TurmericInsufficient evidence
- Vitamin C and DoxycyclineInsufficient evidence
- Vitamin C and MelatoninInsufficient evidence
- Vitamin C and Omega-3 / Fish OilInsufficient evidence
- Vitamin C and SpironolactoneInsufficient evidence
- Vitamin C and Vitamin DInsufficient evidence
- Vitamin C and AmlodipineInsufficient evidence
- Vitamin C and EscitalopramInsufficient evidence
- Vitamin C and Vitamin KInsufficient evidence
- Vitamin C and AshwagandhaInsufficient evidence
- Vitamin C and Folate / Folic AcidInsufficient evidence
- Vitamin C and AspirinInsufficient evidence
- Vitamin C and IbuprofenInsufficient evidence
- Vitamin C and Vitamin EMonitor
- Vitamin C and LosartanInsufficient evidence
- Vitamin C and WarfarinInsufficient evidence
- Vitamin C and ZincInsufficient evidence
- Vitamin C and IronInformational
- Vitamin C and CaffeineInsufficient evidence
- Vitamin C and AtorvastatinMonitor
- Vitamin C and CalciumInsufficient evidence
- Vitamin C and CopperInsufficient evidence
- Vitamin C and CreatineInsufficient evidence
- Vitamin C and MetforminInsufficient evidence
- Vitamin C and SertralineInsufficient evidence
- Vitamin C and Vitamin B12Insufficient evidence