Can I Take These?

Can You Take Levothyroxine and Lisinopril Together?

No documented interaction was identified between lisinopril and levothyroxine in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Levothyroxine page and Lisinopril page for other reviewed interactions and reference information.

What the interaction means

Lisinopril's FDA label does not mention levothyroxine. Levothyroxine's own extensive drug-interaction section (absorption, protein-transport, and metabolism effects) does not name lisinopril or ACE inhibitors.

No documented interaction between Levothyroxine and Lisinopril was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Lisinopril's and levothyroxine's FDA labels were checked directly, full text, in both directions. Neither drug is named in the other's drug-interaction section.

What the sources say

Lisinopril Tablets — FDA Prescribing Information — Prinston Pharmaceutical Inc. (via DailyMed, U.S. National Library of Medicine)Levothyroxine Sodium Capsules — FDA Prescribing Information — YARAL Pharma, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related guides

Related interactions