Vitamin C
Vitamin C (ascorbic acid) is a water-soluble vitamin the body cannot make on its own, needed for collagen synthesis, antioxidant activity, and immune function.
What it is
Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin naturally present in some foods, added to others, and available as a dietary supplement. Humans cannot synthesize it, so it is an essential dietary nutrient. It is required for the biosynthesis of collagen, L-carnitine, and certain neurotransmitters, functions as a physiological antioxidant, supports immune function, and improves the absorption of nonheme iron, the form of iron found in plant-based foods. Insufficient intake causes scurvy.
Food and timing considerations
The best food sources are fruits and vegetables, especially citrus fruits, red and green peppers, kiwifruit, broccoli, strawberries, and Brussels sprouts. Vitamin C is water-soluble and heat-sensitive, so cooking can reduce a food's vitamin C content.
Known interaction categories
- Insufficient evidence
- Monitor
- Informational
Published interaction pages on this site
Informational (1)
Insufficient evidence (32)
- Vitamin C and AmlodipineInsufficient evidence
- Vitamin C and AshwagandhaInsufficient evidence
- Vitamin C and AspirinInsufficient evidence
- Vitamin C and CaffeineInsufficient evidence
- Vitamin C and CalciumInsufficient evidence
- Vitamin C and CiprofloxacinInsufficient evidence
- Vitamin C and CopperInsufficient evidence
- Vitamin C and CoQ10 (Coenzyme Q10)Insufficient evidence
- Vitamin C and CreatineInsufficient evidence
- Vitamin C and DoxycyclineInsufficient evidence
- Vitamin C and EscitalopramInsufficient evidence
- Vitamin C and Folate / Folic AcidInsufficient evidence
- Vitamin C and IbuprofenInsufficient evidence
- Vitamin C and LevothyroxineInsufficient evidence
- Vitamin C and LisinoprilInsufficient evidence
- Vitamin C and LosartanInsufficient evidence
- Vitamin C and MagnesiumInsufficient evidence
- Vitamin C and MelatoninInsufficient evidence
- Vitamin C and MetforminInsufficient evidence
- Vitamin C and Omega-3 / Fish OilInsufficient evidence
- Vitamin C and OmeprazoleInsufficient evidence
- Vitamin C and PotassiumInsufficient evidence
- Vitamin C and ProbioticsInsufficient evidence
- Vitamin C and SertralineInsufficient evidence
- Vitamin C and SpironolactoneInsufficient evidence
- Vitamin C and St. John's WortInsufficient evidence
- Vitamin C and TurmericInsufficient evidence
- Vitamin C and Vitamin B12Insufficient evidence
- Vitamin C and Vitamin DInsufficient evidence
- Vitamin C and Vitamin KInsufficient evidence
- Vitamin C and WarfarinInsufficient evidence
- Vitamin C and ZincInsufficient evidence
Sources
Last reviewed 2026-08-24
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.