Can I Take These?

Can You Take Ibuprofen and Vitamin K Together?

No documented interaction was identified between ibuprofen and vitamin K in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Ibuprofen page and Vitamin K page for other reviewed interactions and reference information.

What the interaction means

Ibuprofen's own FDA label does not name vitamin K anywhere in its Drug Interactions section. MedlinePlus's vitamin K page discusses interactions with blood thinners generally and with vitamin E supplements specifically, but does not mention ibuprofen or NSAIDs.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions. Ibuprofen's antiplatelet/GI-bleeding-risk mechanism is separately documented in this catalog's ibuprofen-warfarin entry; vitamin K's own sources focus on warfarin and vitamin E rather than NSAIDs specifically.

What the sources say

Ibuprofen Tablets, USP — FDA Prescribing Information — Ascend Laboratories, LLC (via DailyMed, U.S. National Library of Medicine)Vitamin K — MedlinePlus, U.S. National Library of Medicine

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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