Can You Take Melatonin and Vitamin K Together?
No documented interaction was identified between melatonin and vitamin K in the sources reviewed.
What the interaction means
NCCIH's melatonin page does not mention vitamin K. MedlinePlus's vitamin K page does not mention melatonin.
No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.
Practical context
Both substances' own current authoritative sources were checked directly, full text, in both directions.
What the sources say
Last reviewed 2026-08-23
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.
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- Vitamin K and LisinoprilInsufficient evidence
- Vitamin K and WarfarinUse caution
- Vitamin K and Vitamin DInsufficient evidence
- Vitamin K and CalciumInsufficient evidence
- Vitamin K and IronInsufficient evidence
- Vitamin K and CiprofloxacinInsufficient evidence
- Vitamin K and CreatineInsufficient evidence
- Vitamin K and SpironolactoneInsufficient evidence
- Vitamin K and St. John's WortInsufficient evidence
- Vitamin K and CaffeineInsufficient evidence
- Vitamin K and CopperInsufficient evidence
- Vitamin K and LevothyroxineInsufficient evidence
- Vitamin K and Vitamin B12Insufficient evidence
- Vitamin K and PotassiumInsufficient evidence
- Vitamin K and TurmericInsufficient evidence
- Vitamin K and ZincInsufficient evidence
- Vitamin K and DoxycyclineInsufficient evidence
- Vitamin K and OmeprazoleInsufficient evidence
- Vitamin K and CoQ10 (Coenzyme Q10)Insufficient evidence
- Vitamin K and MagnesiumInsufficient evidence
- Vitamin K and ProbioticsInsufficient evidence
- Vitamin K and SertralineInsufficient evidence
- Vitamin K and MetforminInsufficient evidence
- Vitamin K and AtorvastatinInsufficient evidence