Melatonin

What it is

Melatonin is a hormone the brain produces in response to darkness, helping with the timing of circadian rhythms and sleep. As a supplement, it's used for situations such as jet lag, delayed sleep-wake phase disorder, and pre-surgery anxiety.

How it is commonly taken

For delayed sleep-wake phase disorder, melatonin is typically taken about 1 hour before the desired bedtime. Melatonin may stay active longer in older adults than in younger people, which can cause daytime drowsiness.

Known interaction categories

• Insufficient evidence

Published interaction pages on this site

• Melatonin and CoQ10 (Coenzyme Q10)Insufficient evidence
• Melatonin and OmeprazoleInsufficient evidence
• Melatonin and WarfarinInsufficient evidence
• Melatonin and AtorvastatinInsufficient evidence
• Melatonin and MagnesiumInsufficient evidence
• Melatonin and CalciumInsufficient evidence
• Melatonin and ProbioticsInsufficient evidence
• Melatonin and CiprofloxacinInsufficient evidence
• Melatonin and SertralineInsufficient evidence
• Melatonin and IronInsufficient evidence
• Melatonin and Vitamin B12Insufficient evidence
• Melatonin and PotassiumInsufficient evidence
• Melatonin and SpironolactoneInsufficient evidence
• Melatonin and ZincInsufficient evidence
• Melatonin and St. John's WortInsufficient evidence
• Melatonin and CopperInsufficient evidence
• Melatonin and LisinoprilInsufficient evidence
• Melatonin and DoxycyclineInsufficient evidence
• Melatonin and MetforminInsufficient evidence
• Melatonin and CreatineInsufficient evidence
• Melatonin and Vitamin DInsufficient evidence
• Melatonin and CaffeineInsufficient evidence
• Melatonin and TurmericInsufficient evidence
• Melatonin and Vitamin KInsufficient evidence
• Melatonin and LevothyroxineInsufficient evidence

Sources