Can I Take These?

Can You Take Aspirin and Vitamin K Together?

No documented interaction was identified between aspirin and vitamin K in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Aspirin page and Vitamin K page for other reviewed interactions and reference information.

What the interaction means

Aspirin's own DURLAZA FDA label does not name vitamin K anywhere in its Drug Interactions section. MedlinePlus's vitamin K page discusses interactions with blood thinners generally and with vitamin E supplements specifically, but does not mention aspirin.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions. Aspirin's antiplatelet mechanism is pharmacologically distinct from warfarin's vitamin-K-dependent mechanism, which may explain why vitamin K's sources focus on warfarin and vitamin E rather than aspirin specifically.

What the sources say

DURLAZA (Aspirin) Extended-Release Capsules — FDA Prescribing Information — New Haven Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)Vitamin K — MedlinePlus, U.S. National Library of Medicine

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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