Can You Take Omega-3 / Fish Oil and Vitamin K Together?

No documented interaction was identified between omega-3 / fish oil and vitamin K in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Omega-3 / Fish Oil page and Vitamin K page for other reviewed interactions and reference information.

What the interaction means

Omega-3's dedicated Interactions with Medications section names only warfarin and similar anticoagulants; vitamin K does not appear anywhere in either omega-3 fact sheet. This repository's existing vitamin K content, built from the MedlinePlus vitamin K page, contains no mention of omega-3 or fish oil.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Omega-3's side was checked directly this pass (both fact sheets, full text). Vitamin K's own MedlinePlus source was not independently re-fetched this pass; this relies on a repository grep of previously-verified vitamin K content, which found no mention of omega-3/fish oil. Note that omega-3 and vitamin K can each separately affect clotting (in opposite directions) when combined with warfarin specifically -- see the omega-3 + warfarin and this catalog's existing vitamin K + warfarin records -- but no source reviewed documents a direct omega-3-to-vitamin-K interaction.

What the sources say

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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