Can I Take These?

Can You Take Ciprofloxacin and Creatine Together?

No documented interaction was identified between ciprofloxacin and creatine in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Ciprofloxacin page and Creatine page for other reviewed interactions and reference information.

What the interaction means

Ciprofloxacin's FDA label does not mention creatine. NCCIH's bodybuilding-supplements page (which covers creatine) does not mention ciprofloxacin/quinolones.

No documented interaction between Ciprofloxacin and Creatine was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both Ciprofloxacin's and Creatine's own current authoritative sources were checked directly, full text, in both directions.

What the sources say

Ciprofloxacin Tablet — FDA Prescribing Information — Rising Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)Bodybuilding and Performance Enhancement Supplements — National Center for Complementary and Integrative Health (NIH)

Last reviewed 2026-08-23

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

Related guides

Related interactions