Can I Take These?

Can You Take Ciprofloxacin and Escitalopram Together?

No documented interaction was identified between escitalopram and ciprofloxacin in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Ciprofloxacin page and Escitalopram page for other reviewed interactions and reference information.

What the interaction means

Escitalopram's FDA label describes a QTc-interval clinical trial that used moxifloxacin (400 mg), a related fluoroquinolone, purely as an assay-sensitivity positive-control comparator arm in a cross-over study design -- moxifloxacin was not administered concurrently with escitalopram to any subject, and the label does not mention ciprofloxacin or quinolones as an interaction concern. Ciprofloxacin's own FDA label does not mention escitalopram, citalopram, SSRIs, serotonin, or antidepressants anywhere; its only QT-related caution is a general geriatric-population note about drug-associated QT effects, naming class IA/III antiarrhythmics, not SSRIs.

No documented interaction was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Both substances' own current authoritative sources were checked directly, full text, in both directions. The moxifloxacin reference on escitalopram's label reflects a clinical-trial design choice (using a drug with known QT effects as a study benchmark), not a documented drug interaction between escitalopram and any fluoroquinolone antibiotic.

What the sources say

Ciprofloxacin Tablet — FDA Prescribing Information — Rising Pharmaceuticals, Inc. (via DailyMed, U.S. National Library of Medicine)LEXAPRO (escitalopram) Tablets and Oral Solution — FDA Prescribing Information — Allergan, Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-24

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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