Can I Take These?

Can You Take Atorvastatin and Doxycycline Together?

No documented interaction was identified between atorvastatin and doxycycline in the sources reviewed.

No documented interaction identifiedEvidence: Moderate

See the full Atorvastatin page and Doxycycline page for other reviewed interactions and reference information.

What the interaction means

Atorvastatin's FDA label's drug-interaction section is mostly CYP3A4-mediated (cyclosporine, gemfibrozil, several CYP3A4 inhibitors, rifampin) -- doxycycline is not among them. Doxycycline's own FDA label does not mention atorvastatin.

No documented interaction between Atorvastatin and Doxycycline was identified in the authoritative sources reviewed. This is not a guarantee that no interaction exists for every dose, formulation, or individual -- it means the sources checked did not document one.

Practical context

Atorvastatin's and doxycycline's FDA labels were checked directly, full text, in both directions. Doxycycline is not a CYP3A4-mediated concern and is not named.

What the sources say

Doxycycline Hyclate — FDA Prescribing Information — Sun Pharmaceutical Industries, Inc. (via DailyMed, U.S. National Library of Medicine)Atorvastatin Calcium Tablet — FDA Prescribing Information — Zydus Pharmaceuticals USA Inc. (via DailyMed, U.S. National Library of Medicine)

Last reviewed 2026-08-25

Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.

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