Calcium
A mineral supplement used to support bone health, taken as calcium carbonate or calcium citrate among other forms.
What it is
Calcium builds and maintains strong bones and also supports muscle movement, nerve communication, blood vessel function, and hormone release. The two most common supplement forms are calcium carbonate and calcium citrate. Food (particularly dairy products) is the preferred source; supplements are used when dietary intake isn't enough.
Food and timing considerations
Calcium carbonate is absorbed best when taken with food. Calcium citrate is absorbed well either with or without food, and is often recommended for people with lower stomach acid. Calcium is generally absorbed best in doses of 500 mg or less at a time, so larger daily amounts are often split across two or more doses.
Known interaction categories
- Insufficient evidence
- Informational
- Monitor
- Use caution
Published interaction pages on this site
Use caution (3)
Informational (1)
Insufficient evidence (28)
- Calcium and AmlodipineInsufficient evidence
- Calcium and AshwagandhaInsufficient evidence
- Calcium and AspirinInsufficient evidence
- Calcium and AtorvastatinInsufficient evidence
- Calcium and CopperInsufficient evidence
- Calcium and CoQ10 (Coenzyme Q10)Insufficient evidence
- Calcium and CreatineInsufficient evidence
- Calcium and EscitalopramInsufficient evidence
- Calcium and Folate / Folic AcidInsufficient evidence
- Calcium and IbuprofenInsufficient evidence
- Calcium and LisinoprilInsufficient evidence
- Calcium and LosartanInsufficient evidence
- Calcium and MagnesiumInsufficient evidence
- Calcium and MelatoninInsufficient evidence
- Calcium and MetforminInsufficient evidence
- Calcium and Omega-3 / Fish OilInsufficient evidence
- Calcium and PotassiumInsufficient evidence
- Calcium and ProbioticsInsufficient evidence
- Calcium and SertralineInsufficient evidence
- Calcium and SpironolactoneInsufficient evidence
- Calcium and St. John's WortInsufficient evidence
- Calcium and TurmericInsufficient evidence
- Calcium and Vitamin B12Insufficient evidence
- Calcium and Vitamin CInsufficient evidence
- Calcium and Vitamin EInsufficient evidence
- Calcium and Vitamin KInsufficient evidence
- Calcium and WarfarinInsufficient evidence
- Calcium and ZincInsufficient evidence
Related guides
Sources
Last reviewed 2026-08-22
Medical information disclaimer: this information is general and educational. It does not diagnose conditions, prescribe treatment, or determine whether a combination is safe for you personally. Follow your prescription label and ask a pharmacist or clinician before starting, stopping, or combining products. Full disclaimer.